Erin E Crotty, MD

Erin E Crotty, MD

Specialties

  • Children's Title: Attending Physician, Pediatric Hematology/Oncology and Bone Marrow Transplant
  • Academic Title: Assistant Professor, Department of Pediatrics, University of Washington School of Medicine
  • Research Title: Principal Investigator, Ben Towne Center for Childhood Cancer Research
  • Research Center: Ben Towne Center for Childhood Cancer Research
  • On Staff Since: July 2020
"I’m motivated by the connections I make with each patient and committed to improving their daily experience living with and beyond a cancer diagnosis. I believe excellence in oncology care is built on team science, and I’m privileged to work with an incredible multidisciplinary team in Seattle, where translating discoveries from the lab bench to the patient is a familiar reality."

  • Biography

    Erin Crotty, M.D. is an attending physician and pediatric oncologist in the Brain Tumor Program at Seattle Children's Hospital and Assistant Professor at the University of Washington School of Medicine. She cares for children and adolescents with brain and spinal cord tumors, and is the medical lead for the Retinoblastoma Program alongside oncologic ophthalmologist, Andrew Stacey, M.D. She is involved locally and internationally in early phase clinical trials for children with brain tumors and serves as site Principal Investigator for the Pacific Pediatric Neuro-oncology Consortium (PNOC). Her research and clinical interests focus on implementing new immunotherapies, like CAR T cells, and precision medicine approaches for difficult-to-treat brain tumors.

    Dr. Crotty completed her pediatric residency training at Children's National Medical Center in Washington, D.C. and returned home to the west coast for her hematology/oncology fellowship at Seattle Children's Hospital/University of Washington, where she completed additional translational research training in the laboratory of James Olson, M.D.,Ph.D. at the Fred Hutchinson Cancer Research Center, studying novel protein therapeutics.

    Board Certification(s)

    Pediatric Hematology-Oncology
    Pediatrics

    Education

    George Washington University School of Medicine & Health Sciences, Washington, DC

    Residency

    Children's National Medical Center, Washington, DC

    Fellowship

    University of Washington School of Medicine, Seattle, WA

    Clinical Interests

    Brain and spinal cord tumors of childhood; high-grade glioma (HGG), diffuse intrinsic pontine glioma (DIPG); diffuse midline glioma (DMG); medulloblastoma, ependymoma, CAR T cell immunotherapy; early phase clinical trials; Retinoblastoma

    Research Description

    Dr. Crotty's research interests include immuno-oncology and precision medicine approaches for children with brain and spinal cord tumors. Dr. Crotty is particularly interested in the translation of promising therapies from the lab bench into innovative clinical trials for patients. She collaborates with international cancer consortium members in the design and implementation of clinical research.

    Dr. Crotty's prior work in the Olson Laboratory at the Fred Hutchinson Cancer Center (now located at Seattle Children's Research Institute) studying novel immunotherapy for medulloblastoma provided the preclinical foundation for an upcoming international CONNECT Phase I clinical trial, which she will lead as co-Principal Investigator. In 2022, she was awarded the Children's Cancer Research Fund Emerging Scientist Award to study a novel cell-free DNA sequencing technique to reliably detect residual disease left over after treatment in the cerebrospinal fluid (CSF). For children with brain tumors, this platform could enable personalized treatment with reduced toxicity.

    Research Focus Area

    Cancer biology, Immunotherapy, CAR-T cells, Epigenetic modifying agents, cell-free DNA, Early phase clinical trials for pediatric brain tumors

  • Related Resources

    • The Olson Lab

      The Olson lab identifies, prioritizes, and advances therapeutics into clinical trials for children with brain cancer, with increasing focus on types of brain tumors that are uncommon and have the greatest need for translational research.

    • Retinoblastoma Program

      Learn about treatment options for retinoblastoma, cancer in the lining of the eye. At Seattle Children’s, your child will get care from a team of specialists experienced in treating retinoblastoma. We provide the most advanced treatments in our region, including intra-arterial chemotherapy.

  • Patient Testimonials

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  • Awards and Honors

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  • Publications

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  • Clinical Trials and Research

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