Selected Publications
Listed below is a selection of recent publications from the Stuart Lab.
Systems analysis of immune responses to attenuated P. falciparum malaria sporozoite vaccination reveals excessive inflammatory signatures correlating with impaired immunity. Du Y, Hertoghs N, Duffy FJ, Carnes J, McDermott SM, … Stuart KD et al. PLoS Pathog. 2022 Feb 2;18(2):e1010282.
Domain function and predicted structure of three heterodimeric endonuclease subunits of RNA editing catalytic complexes in Trypanosoma brucei. Carnes J, McDermott SM, Lewis I, Tracy M, Stuart K. Nucleic Acids Res. 2022 Sep 23;50(17):10123-10139.
Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case-control study. Moncunill G, Carnes J, Chad Young W, … Stuart K, Gottardo R et al. Elife. 2022 Jan 21;11:e70393.
Preimmunization correlates of protection shared across malaria vaccine trials in adults. Neal ML, Duffy FJ, Du Y, Aitchison JD, Stuart KD. NPJ Vaccines. 2022 Jan 14;7(1):5.
Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers. Duffy FJ, Du Y, Carnes J, … Stuart K et al. Malar J. 2021 Jul 9;20(1):308.
Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei. McDermott SM, Carnes J, Stuart K. RNA. 2019 Sep;25(9):1150-1163.
Nuclear Phosphatidylinositol 5-Phosphatase Is Essential for Allelic Exclusion of Variant Surface Glycoprotein Genes in Trypanosomes. Cestari I, McLeland-Wieser H. Stuart K. Mol Cell Biol. 2019 Jan 16;39(3):e00395-18.
Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period. Rothen J, Murie C, Carnes J, … Stuart K, et al. PLoS One. 2018; 13(6): e0199392.
Controlled human malaria infection leads to long-lasting changes in innate and innate-like lymphocyte populations. Mpina M, Maurice N, Yajima M, … Stuart KD, et al. J Immunol. 2017 Jul 1;199(1):107-118.
Identification by Random Mutagenesis of Functional Domains in KREPB5 That Differentially Affect RNA Editing Between Life Cycle Stages of Trypanosoma brucei. McDermott SM, Carnes J, Stuart K. Mol Cell Biol. 2015 Dec;35(23):3945-61.