Selected Publications
Listed below is a selection of recent publications from the Urdahl Lab.
Alveolar macrophages provide an early Mycobacterium tuberculosis niche and initiate dissemination. Cohen SB, Gern BH, Delahaye JL, Adams KN, Plumlee CR, Winkler JK, Sherman DR, Gerner MY, Urdahl KB. Cell Host Microbe. 2018 Sep 12;24(3):439-446.e4.
Antigen availabilityshapes T cell differentiation and function during tuberculosis. Moguche AO, Musvosvi M, Penn-Nicholson A, ... Sherman DR, Urdahl KB. Cell Host Microbe. 2017 Jun 14;21(6):695-706.e5.
Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung. Woodworth JS, Cohen SB, Moguche AO, Plumlee CR, Agger EM, Urdahl KB, Andersen P. Mucosal Immunol. 2017 Mar;10(2):555-564.
MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181.
TB vaccines; promoting rapid and durable protection in the lung. Andersen P, Urdahl KB. Curr Opin Immunol. 2015 Aug;35:55-62.
ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis. Moguche AO, Shafiani S, Clemons C, … Urdahl KB. J Exp Med. 2015 May 4;212(5):715-28.
Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids. Cambier CJ, Takaki KK, Larson RP, Hernandez RE, Tobin DM, Urdahl KB, Cosma CL, Ramakrishnan L. Nature. 2014 Jan 9;505(7482):218-22.
Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis. Urdahl KB. Semin Immunol. 2014 Dec;26(6):578-87
Pathogen-specific Treg cells expand early during mycobacterium tuberculosis infection but are later eliminated in response to Interleukin-12. Shafiani S, Dinh C, Ertelt JM, … Urdahl KB. Immunity. 2013 Jun 27;38(6):1261-70.
Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis. Shafiani S, Tucker-Heard G, Kariyone A, Takatsu K, Urdahl KB. J Exp Med. 2010 Jul 5;207(7):1409-20.