Kalume Laboratory

Selected Publications

Dr. Franck Kalume has authored a number of research papers on epilepsy and other neurological disorders, including the selected publications listed below. To see more of Kalume's publications, view a complete list on PubMed.

  1. Kalume F, Westenbroek RE, Cheah CS, Yu FH, Oakley JC, Scheuer T, Catterall WA. Sudden unexpected death in a mouse model of Dravet syndrome. The Journal of Clinical Iinvestigation 123: 1798-808, 2013.
  2. Kalume F. Sudden unexpected death in Dravet syndrome: respiratory and other physiological dysfunctions. Respiratory Physiology & Neurobiology 189: 324-8, 2013.
  3. Cheah CS, Yu FH, Westenbroek RE, Kalume FK, Oakley JC, Potter GB, Rubenstein JL, Catterall WA. Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome. Proceedings of the National Academy of Sciences of the United States of America 109: 14646-51, 2012.
  4. Dutton SBB, Sawyer NT, Kalume F, Jumbo-Lucioni P, Borges K, Catterall WA, Escayg A. Protective effect of the ketogenic diet in Scn1a mutant mice. Epilepsia 52: 2050-6, 2011.
  5. Oakley JC, Kalume F, Catterall WA. Insights into pathophysiology and therapy from a mouse model of Dravet syndrome. Epilepsia 52 Suppl 2: 59-61, 2011.
  6. Catterall WA, Kalume F, Oakley JC. NaV1.1 channels and epilepsy. The Journal of Physiology 588: 1849-59, 2010.
  7. Oakley JC, Kalume F, Yu FH, Scheuer T, Catterall WA. Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy. Proceedings of the National Academy of Sciences of the United States of America 106: 3994-9, 2009.
  8. Kalume F, Yu FH, Westenbroek RE, Scheuer T, Catterall WA. Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy. The Journal of Neuroscience 27: 11065-74, 2007.
  9. Yu FH, Mantegazza M, Westenbroek RE, Robbins CA, Kalume F, Burton KA, Spain WJ, McKnight GS, Scheuer T, Catterall WA. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nature Neuroscience 9: 1142-9, 2006.